Within the fibrous regions, pre-engineered vascular channels are incorporated to guide host vascular ingrowth, resulting in a 2.6-fold increase in neovascular density compared to no-channel scaffolds. When transplanted via end-to-end anastomosis with native tracheae, the vascularized grafts exhibit enhanced survival and functional integration, offering a robust strategy for tracheal tissue engineering and segmental airway reconstruction.
Countstar Connection
Using Countstar Castor S1, the researchers measured cell measurements in the study samples during quality assessment for the reported research.