Spica M1
Open the Door to Your Live-Cell Analysis.
Live Cell Analysis
In-Incubator System
Fluorescence
Mammalian Cells
Advanced Cell Models
Cell Health & Quality Control
Meet the Spica M1. A dedicated, single-plate platform equipped with flagship AI. Uncover the complete dynamic narrative of your cells from Day 0 to definitive discovery—without ever disturbing their environment.
Your Dedicated Gateway
to Kinetic Clarity
The Spica M1 opens the door to uncompromising kinetic analysis directly at your lab bench. Pairing a precise, dedicated single-plate imaging system with the exact same high-speed, premium 3-channel optics guarantees uninterrupted availability for your most critical assays.  It is the perfect platform for meticulous, focused research, offering the agility needed for rapid assay development.
Native Incubator Integration
Operates completely inside standard incubators to preserve absolute physiological integrity.
Dedicated Single-Plate Architecture
Open the door to uninterrupted workflows. Maintain complete control over your kinetic runs without the scheduling conflicts of a shared system.
Real-Time Kinetic Analysis
Generate growth curves and actionable metrics long before the run is complete.
Adaptive Dual-Engine Intelligence
Toggle seamlessly between rapid routine assays and advanced, bias-free AI modeling.
Enterprise-Wide Remote Access
Enable multiple users to concurrently monitor assays, schedule scans, and export results from anywhere on your local network.
Modern, Intuitive Software
Set up complex assays in minutes with an interface designed to be helpful, not authoritative.
Spica Ecosystem
The Spica Ecosystem: Which System is Right for You?
Whether you are optimizing a novel assay or screening thousands of compounds, the Spica platform scales with your science. Both systems feature our premium optics and the advanced Stellar AI intelligence layer.
Feature
Spica M1
Spica M6
Ideal For
Dedicated projects, assay development, and focused kinetic tracking.
Multi-user environments, high-throughput screening, and core facilities.
Throughput
1 Microplate
6 Microplates
Optical Power
3-Channel Multiparametric
4-Channel Multiparametric
Analysis Software
Standard Engine + Stellar AI Layer
Standard Engine + Stellar AI Layer
Footprint
Ultra-Compact In-Incubator (>160L)
Compact In-Incubator (>200L)
Product Details
Premium Optics in a
Dedicated Footprint
The Spica M1 features a high-precision optical drive designed to capture every biological nuance without compromise.
Minimal Cell Disruption:
Optics move beneath the deck while your plate remains stationary, eliminating fluid shear stress.
Multiplex Fluorescence
Cover a broad spectral range. Confidently track dynamic cellular events by multiplexing up to 3 distinct colors simultaneously.
Automated Magnification
Assign 7.5x, 10x, and 15x magnifications to your assay without manually swapping lenses.
User-Defined Z-Stacking:
Set precise focal planes to capture custom z-stacks, keeping complex 3D organoids in perfect focus.
Open the Door to Transparent AI
Traditional imaging software locks you into rigid algorithms. The Spica M1 breaks the black box, giving you an adaptive, two-tiered software ecosystem that puts you in control.
The Standard Engine:
Rapid, one-click quantification for routine workflows like confluence and cell health assays
The Stellar AI Layer:
Advanced, no-code customization. Easily train bespoke models and define tailored metrics across your microplate.
Learn more about Stellar AI
Applications
Translating Curiosity into Clarity Across Every Field
Oncology & Immuno-Oncology
Visualize complex tumor microenvironments and immune responses over time.

Key Assays:
Immune Cell Killing
Phagocytosis & Efferocytosis
Apoptosis & Cytotoxicity.
Targeted Therapeutics & Validation
Track multiplexed dose-response assays to confidently validate target engagment.
Key Assays:
Dose-Response Kinetics
Cell Cycle Dynamics
Antibody Internalization
3D Biology & Organoids
Track the growth, viability, and differentiation of complex organoids over weeks.

Key Assays:
Organoid Growth & Viability
3D Morphological Profiling
Tumor Spheroid Invasion
Cell Line Development & Optimization
Streamline generation and maintenance with continuous proliferation tracking.

Key Assays:
Clonal Outgrowth & Confluence
Reporter Gene Expression
Transfection Efficiency
Stem Cell Research
Quantify lineage commitments and expansion rates as your cultures mature.
Key Assays:
Pluripotency Marker Expression
Embryoid Body (EB) Formation
Stem Cell Expansion
Cell & Gene Therapy
Continuously monitor target engagement to validate the persistence of engineered therapies.
Key Assays:
CAR-T Cell Expansion
Immune Cell Clustering & Target Engagement
Transduction Efficiency
Tech Specs
Specifications & related products
Category
Specification
Camera
High-sensitivity CMOS camera, 3200×2200, 7.1MP
Fluorescence Channel
Ex: 375/28,   Em: 430/30nm
Ex: 470/20,   Em: 515/40nm
Ex: 560/25,   Em: 630/70nm
Optical magnification and resolution
7.5×: 0.6 µm/pixel
10×: 0.45 µm/pixel
15×: 0.30 µm/pixel
Field of view
7.5×: 1.92×1.32mm
10×: 1.44×0.99mm
15×: 0.96×0.66mm
Focus Mode
Laser focus and image-based focus
Imaging mode
Bright-field microscopy, Fluorescence microscopy, Z-axis layer
scanning
Supported consumables
6-384 well plates, 35/60/100mm dishes, T25/T75 flasks, organ-
on-a-chip microfluidic chips
Analysis Algorithm
AI image analysis and conventional image processing
Exported video format
AVI, MP4
Exported image format
JPEG, TIFF, BMP, PNG
Exported data format
XLSX, CSV
Dimensions
300(L)×300(W)×337(H) mm
Ready to
Open the Door to your Live Cell Analysis?