WWC proteins-mediated compensatory mechanism restricts schwannomatosis driven by NF2 loss of function.
Science advances
Wang X, Zhu R, Yu P, Qi S, Zhong Z, Jin R, Wang Y, Gu Y, Ye D, Chen K, Shu Y, Wang Y, Yu FX.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Cancer Research
Single-Cell Analysis
No items found.
Key Finding
Moreover, a cell line from mouse schwannomas and a syngeneic tumor model in immune-competent mice are established. Furthermore, a screen using established models has identified candidate drugs that effectively suppress schwannoma progression.
Countstar Connection
Countstar (model not specified) provided the instrument readout for cell viability in the study's cell samples before single-cell analysis for the reported research.
