WHSC1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Activating mTORC1 Signaling.
OncoTargets and therapy
Dai J, Jiang L, Qiu L, Shao Y, Shi P, Li J.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2020
Cancer Research
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Key Finding
Survival analyses revealed that WHSC1 upregulation predicted poor overall survival and higher recurrence rates in patients with HCC. Functional studies revealed that WHSC1 significantly stimulated HCC proliferation, migration, and invasion in vitro and in vivo.
Countstar Connection
Within the research, Countstar (model not specified) assessed cell concentration in the study's cell samples during migration assessment in the 2020 OncoTargets and therapy study.