WD40 repeat 43 mediates cell survival, proliferation, migration and invasion via vimentin in colorectal cancer.
Cancer cell international
Li Z, Feng M, Zhang J, Wang X, Xu E, Wang C, Lin F, Yang Z, Yu H, Guan W, Wang H.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2021
Cancer Research
No items found.
Key Finding
Finally, the authors explored potential downstream proteins or pathways and established subcutaneous xenograft model to verify the findings. In addition, it was found that WDR43 knockdown inhibited vimentin (VIM) expression in CRC cells and overexpression of VIM can partially reverse the effects of WDR43 both in vitro and in vivo.
Countstar Connection
The study's cell samples underwent cell-count assessment with Countstar (model not specified) during migration assessment in the 2021 Cancer cell international study.
