Upregulation of DRG protein TMEM100 facilitates dry-skin-induced pruritus by enhancing TRPA1 channel function.
Acta biochimica et biophysica Sinica
Pan C, Jiao Y, Kong D, Deng H, Xu S, Tang D, Yin W, Gao P, Yu W, Fan Y, Wen D.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2022
Single-Cell Analysis
No items found.
Key Finding
The study's strongly suggest that TMEM100 protein in DRG is the main facilitating factor for dry-skin-related chronic itch, and specific suppression of TMEM100 in DRG could be a novel effective treatment strategy for patients who suffer from dry skin-induced itch.
Countstar Connection
Cell viability was measured in the study's cell samples with Countstar (model not specified) before single-cell analysis in the 2022 Acta biochimica et biophysica Sinica study.
