Transfer of IGF2BP3 Through Ara-C-Induced Apoptotic Bodies Promotes Survival of Recipient Cells.
Frontiers in oncology
Gou J, Li H, Bi J, Pang X, Li X, Wang Y.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2022
Immunology
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Key Finding
High IGF2BP3 level in ABs from MDS/AML patient plasma was correlated with poor overall survival. The findings demonstrate that AB-derived IGF2BP3 plays an essential role in acquired Ara-C resistance in MDS/AML patients, and is a potential therapeutic target for suppression of Ara-C resistance.
Countstar Connection
The study obtained cell-count measurements from the study's cell samples using a Countstar instrument during sample-quality assessment.
