Transcriptional silencing of ETS-1 abrogates epithelial-mesenchymal transition resulting in reduced motility of pancreatic cancer cells.
Oncology reports
Li C, Wang Z, Chen Y, Zhou M, Zhang H, Chen R, Shi F, Wang C, Rui Z.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2015
Cancer Research
Immunology
Stem Cell Research
No items found.
Key Finding
The authors detected reduced N-cadherin and vascular endothelial growth factor yet higher E-cadherin expression in the ETS-1-silenced cells compared with the control group. These suggest that analysis of ETS-1 expression levels may provide an avenue for evaluating prognosis in pancreatic cancer.
Countstar Connection
Using a Countstar instrument, the study measured cell numbers in the study's cell samples during sample-quality assessment.
