SCIENTIFIC EVIDENCE

Transcription Factor EBF1 Over-Expression Suppresses Tumor Growth in vivo and in vitro via Modulation of the PNO1/p53 Pathway in Colorectal Cancer

Frontiers in Oncology

Zhiqing Shen, Youqin Chen, Li Li, Liya Liu, Meizhong Peng, Xiaoping Chen, Xiangyan Wu, Thomas J. Sferra, Meizhu Wu, Xiaoying Lin, Ying Cheng, Jianfeng Chu, Aling Shen, Jun Peng

Publication Overview

Key findings, Countstar context, and access to the original paper.

2020

Cell Counting & Viability

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Key Finding

The authors examined EBF1 over-expression in colorectal cancer models. They report suppressed tumour growth in vitro and in vivo and associate the effects with modulation of the PNO1/p53 pathway, indicating a potential tumour-suppressive role for EBF1 in this setting.

Countstar Connection

Counted trypsinized colorectal cancer cells after trypan-blue staining.

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