Therapeutic Black Phosphorus Nanosheets Elicit Neutrophil Response for Enhanced Tumor Suppression.

Moreover, bulk and single-cell RNA sequencing indicate that BP-PEG is mainly taken up by macrophages, leading to the release of inflammatory factors such as IL1A and CXCL2, which enhance neutrophil recruitment and activation, thereby amplifying the antitumor immune response.

The research used Countstar (model not specified) for cell-count assessment in the study's cell samples before downstream analysis for the cancer-model experiments.