The validation of quality attributes in Primary Human Hepatocytes Standard.
Cell regeneration (London, England)
Peng Z, Wu J, Zhang X, Jia X, Wu Z, Dai H, Huang D, Cheng X, Pan G, Huang R.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Single-Cell Analysis
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Key Finding
Single cell transcriptomic analysis also revealed significant cell heterogeneity across the different batches, with the proportions of hepatocytes ranging from 69.2% to 98.9%. These confirmed the robustness of most quality attributes in current CSCB standard, while highlighting the need to refine remaining parameters to enhance its practical applicability.
Countstar Connection
The research used Countstar (model not specified) for cell assessment in cell suspensions before single-cell analysis for the reported research.