SCIENTIFIC EVIDENCE

The single-cell immune landscape of HIV-associated aggressive B-cell lymphoma.

Journal of the National Cancer Center
Zhang X, Yang Z, Xie X, Li J, Xiao Q, Xu G, Ma B, Xie X, Liu Y, Zhai L, Tang Y, Fu H, He S, Liu T, Huang D, Zeng C, Zhou Y, Hu R, Guo B, Wang C, Liang S, Luo Q, Lv J, Nan Y, Li J, Li Q, Wang S, Wu Y, Liu Y.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2025
Cancer Research
Immunology
Microbiology
Single-Cell Analysis
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Key Finding
Human immunodeficiency virus (HIV)-associated lymphomas (HAL), mainly aggressive B-cell lymphomas, pose a significant challenge in cancer research due to their multifaceted pathogenesis and aggressive clinical course. The findings clearly indicate that HAL differs significantly from non-HAL, ranging from malignant B cells to the immune microenvironment.
Countstar Connection
Using Countstar Rigel S2, the researchers measured cell number and viability in the study's cell samples before single-cell analysis for the study's single-cell analysis.
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