The first embryonic landscape of G-quadruplexes related to myogenesis.
BMC biology
Guo L, Huang W, Wen Q, Zhang S, Bordbar F, Xiao Z, Nie Q.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2024
Cell Counting & Viability
No items found.
Key Finding
Notably, the NFATC2 promoter region sequence is confirmed to form a G4 structure, reducing promoter mCpG content and upregulating NFATC2 transcriptional activity. This comprehensive study unravels the first embryonic genomic G4s landscape, highlighting the regulatory role of NFATC2 G4 in orchestrating transcriptional activity through promoter DNA methylation during myogenesis.
Countstar Connection
Countstar (model not specified) was the instrument used to assess cell numbers in the study's cell samples during the study's growth assessment.
