SCIENTIFIC EVIDENCE

TCF-1 and TOX regulate the memory formation of intestinal group 2 innate lymphoid cells in asthma

Nature Communications
Kaifan Bao, Xiaoqun Gu, Yajun Song, Yijing Zhou, Yanyan Chen, Xi Yu, Weiyuan Yuan, Liyun Shi, Jie Zheng, Min Hong

Publication Overview

Key findings, Countstar context, and access to the original paper.
2024
Cell Counting & Viability
Single-Cell Analysis
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Key Finding
The study examines how TCF-1 and TOX shape the memory formation of intestinal group 2 innate lymphoid cells in asthma. It identifies transcriptional regulation associated with ILC2 persistence and links these cells to allergic airway inflammation in experimental systems.
Countstar Connection
Measured total bronchoalveolar lavage fluid cells in a mouse asthma model.
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