SCIENTIFIC EVIDENCE

Targeting NUFIP1 Suppresses Growth and Induces Senescence of Colorectal Cancer Cells

Frontiers in Oncology
Aling Shen, Meizhu Wu, Liya Liu, Youqin Chen, Xiaoping Chen, Mingkai Zhuang, Qiurong Xie, Ying Cheng, Jiapeng Li, Zhiqing Shen, Lihui Wei, Jianfeng Chu, Thomas J. Sferra, Xiuli Zhang, Nanhui Xu, Li Li, Jun Peng, Fenglin Chen

Publication Overview

Key findings, Countstar context, and access to the original paper.
2021
Cell Counting & Viability
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Key Finding
This colorectal cancer study investigated the role of NUFIP1 in tumour-cell growth and senescence. The authors report that reducing NUFIP1 suppressed growth and induced senescence-associated effects, linking the phenotype to altered ribosome-biogenesis-related signalling.
Countstar Connection
Measured trypan-blue-stained colorectal cancer cells in growth experiments.
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