T Gene Mutation Leads to Short Tail in Sheep via Premature AER Degeneration: Single-Cell Evidence from Embryos.
Animals: an open access journal from MDPI
Su H, Yang Y, Zuo Y, Song Y, Wang D, Zhang M, Cao G.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2026
Single-Cell Analysis
No items found.
Key Finding
In the mouse model, mutant T expression was reduced, and expression dynamics of WNT5B and FGF8 were perturbed, corroborating the sheep findings; however, homozygous T mutation causes embryonic lethality in mice but not in sheep, indicating species-specific differences.
Countstar Connection
Within the study, Countstar Rigel S5 measured cell concentration and viability in the study's cell samples during preparation for single-cell or single-nucleus analysis.
