In the mouse model, mutant T expression was reduced, and expression dynamics of WNT5B and FGF8 were perturbed, corroborating the sheep findings; however, homozygous T mutation causes embryonic lethality in mice but not in sheep, indicating species-specific differences.
Countstar Connection
Within the study, Countstar Rigel S5 measured cell concentration and viability in the study's cell samples during preparation for single-cell or single-nucleus analysis.