Stress-induced premature senescence in high five cell cultures: a principal factor in cell-density effects.
Bioresources and bioprocessing
Min R, Zhang D, He M, Chen J, Yi X, Zhuang Y.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2024
Microbiology
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Key Finding
The findings suggested that stress-induced premature senescence in High Five cell cultures, resulting in reduced energy metabolism and protein synthesis capabilities, was a critical factor contributing to cell density effects, and ultimately affecting virus production.
Countstar Connection
The researchers assessed cell concentration, viability, and size in the study's cell samples with Countstar (model not specified) during cell-culture monitoring.
