SCIENTIFIC EVIDENCE

Stress granule clearance mediated by V-ATPase-interacting protein NCOA7 mitigates ovarian aging.

Nature aging
Dong T, Li N, Wang H, Zhu H, Gao Y, Liu Y, Fang F, Fu X, Si P, Li C, Li M, Wang F, Zhao S, Guo T, Cui L, Jiang X, Liu X, Zhao H, Qin Y, Chen ZJ, Lou H, Jiao X.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2025
Cell Counting & Viability
No items found.
Key Finding
The study identified deleterious mutations and decreased expression of NCOA7, a stress-response protein related to granulosa cell senescence in women with physiological and pathological ovarian aging. This study depicts a mechanism for ovarian resilience to stress and provides potential targets for therapeutic strategies to alleviate ovarian aging.
Countstar Connection
Countstar (model not specified) supported assessment of cell numbers in cell suspensions during growth assessment in the 2025 Nature aging study.
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