SCIENTIFIC EVIDENCE

SLC4A7 Drives NSCLC Progression and Immune Evasion via pH Dysregulation: Its Targeting Synergizes with Anti-PD-1/L1 Therapy.

International journal of biological sciences
Qin H, Tang D, Li Z, Yang F, Wang J, Liu X, Chen C, Gao W.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2026
Cancer Research
Immunology
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Key Finding
Both in vivo and in vitro data demonstrate that the alkalinization of the TME induced by Slc4a7 knockout enhances the infiltration and function of cytotoxic T cells, significantly inhibiting tumor growth.
Countstar Connection
Countstar Rigel S2 was used to quantify cell numbers in the study's cell samples during sample-quality assessment.
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