SIRT1 Modulates the Photodynamic Anticancer Activity of 5,10,15-Triethoxycarbonyl P(V) Corrole in Hepatocellular Carcinoma.
Pharmaceuticals (Basel, Switzerland)
Liu Y, Zheng J, Zhu J, Xian X, Zhang Z, Zhang H.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Cancer Research
No items found.
Key Finding
Photodynamic therapy (PDT) using 5,10,15-triethoxycarbonyl P(V) corrole ( 1-P ) shows promise, but its molecular mechanisms and regulatory factors, particularly the role of SIRT1, are poorly understood. SIRT1 is a critical modulator of 1-P activity, highlighting its potential as a therapeutic target to enhance PDT efficacy in HCC.
Countstar Connection
Using Countstar (model not specified), the study assessed cell numbers in the study's cell samples during quality assessment in the 2025 Pharmaceuticals study.
