Single-cell transcriptomics reveals novel chondrocyte and osteoblast subtypes and their role in knee osteoarthritis pathogenesis.

A single-cell atlas of the osteochondral composite tissue was established. The number of H-type vessels was increased in the subchondral bone, recruiting osteoprogenitor cells and facilitating osteogenesis in KOA mice.

Countstar Rigel S2 measured cell number and viability in the study's cell samples before single-cell analysis in the 2025 Signal transduction and targeted therapy study.