SCIENTIFIC EVIDENCE

Single-Cell Transcriptomics of Human Pericarotid Lymph Nodes Indicating Stability of Carotid Atherosclerotic Plaques.

Journal of the American Heart Association
Sun T, Wu Y, Liu G, Xue Z, Yu M, Mao B, Han M, Liang X, Ling L, You N, Ji L, Liu H, Xu C, Qin Z, Zhao P, Wang D.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2025
Immunology
Single-Cell Analysis
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Key Finding
Patients with symptomatic carotid atherosclerosis had more enlarged pericarotid LNs ( P + macrophage infiltration ( P P P Enlarged pericarotid LNs are potential biomarkers for plaque instability and recent ischemic events. This study provides a comprehensive single-cell transcriptomic landscape of human LNs in atherosclerosis.
Countstar Connection
The study obtained cell-concentration and viability measurements from the study's cell samples using Countstar (model not specified) during preparation for single-cell or single-nucleus analysis.
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