SCIENTIFIC EVIDENCE

Single-Cell Transcriptome Profiling Reveals Multicellular Ecosystem of Nucleus Pulposus during Degeneration Progression.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Tu J, Li W, Li W, Yang S, Yang P, Yan Q, Wang S, Lai K, Bai X, Wu C, Ding W, Cooper-White J, Diwan A, Yang C, Yang H, Zou J.

Publication Overview

Key findings, Countstar context, and access to the original paper.

2022

Single-Cell Analysis

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Key Finding

Their immunosuppressive function and alleviation effects on NPCs' matrix degradation are revealed in vitro. Collectively, this study reveals the NPC-type complexity and phenotypic characteristics in NP, thereby providing new insights and clues for IVDD treatment.

Countstar Connection

Countstar (model not specified) measured cell viability in the study's cell samples before single-cell analysis in the 2022 Advanced science study.

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