Single-cell transcriptome atlas of spontaneous dry age-related macular degeneration in macaques.
Fundamental research
Su W, Gao Y, Jia X, Chen X, Wu J, Wen Y, Shi Y, Zhu Y, Zhuo Y.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Single-Cell Analysis
No items found.
Key Finding
The authors also found that the disruption of iron homeostasis and ferroptosis could promote SD-AMD pathogenesis in neural cells. Further experimentation revealed that a ferroptosis inhibitor exerted a profound rescuing effect in SD-AMD mouse models.
Countstar Connection
Countstar (model not specified) supported measurement of cell number and viability in the study's cell samples during preparation for single-cell or single-nucleus analysis.
