Single-cell RNA sequencing reveals endothelial cell heterogeneity and Sox18-mediated EndMT in abdominal aortic aneurysm.
Theranostics
Wu X, Liu X, Cheng Y, Zhang Y, Shi D, Shi Y, Liu X, Feng J, Long A, Hu W, Yang Z.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Single-Cell Analysis
No items found.
Key Finding
The data reveal the heterogeneity and transcriptional signatures of ECs in AAA at single cell solution, and demonstrate the previously unrecognized role of Sox18-mediated EndMT in AAA, providing novel insights and a promising therapeutic target for AAA intervention.
Countstar Connection
For single-cell suspensions, Countstar (model not specified) supplied cell measurements during preparation for single-cell or single-nucleus analysis.
