Single-Cell RNA Sequencing Reveals Cellular Heterogeneity in an Acral Amelanotic Melanoma After Immunotherapy Treatment.
Clinical, cosmetic and investigational dermatology
Zhuang L, Tian J, Lai B, Zhang G, Li H.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2023
Cancer Research
Immunology
Single-Cell Analysis
No items found.
Key Finding
Ki-67 immunohistochemical staining revealed that the pigmented melanoma cells had a higher proliferative ability than the amelanotic cells. scRNA-seq identified three cell clusters: amelanotic cell cluster 1, amelanotic cell cluster 2, and pigmented cell cluster.
Countstar Connection
Countstar (model not specified) measured cell viability in the study's cell samples before single-cell analysis in the 2023 Clinical, cosmetic and investigational dermatology study.
