Single-cell RNA sequencing and proteomics uncover SIRPα-CD47 immune checkpoint and glycolysis-driven immune evasion in cardiac myxoma.
Frontiers in immunology
Zhu X, Gao Q, Dai X, Sun B, Li Y, Zhai H, Shan C.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Bioprocessing
Cancer Research
Immunology
Single-Cell Analysis
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Key Finding
Additionally, this work demonstrated that the glycolysis pathway is significantly activated and fuels CM cell growth. These work's findings not only deepen the current understanding of CM's biological nature but also offer vital theoretical foundations for developing safer, more effective CM therapies.
Countstar Connection
Researchers used Countstar Rigel S2 to assess cell number and viability in the study's cell samples during preparation for single-cell or single-nucleus analysis.
