Single-Cell RNA-Seq Revealed the Immune Microenvironment Reprogramming by Dexmedetomidine Treatment in Ischemic Stroke.
Molecular neurobiology
Zhang W, Wang X, Zhang B, Yi M, Lu Y, Wang S, Zhang J, Zhang G.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Immunology
Single-Cell Analysis
No items found.
Key Finding
Mechanistically, the authors identified HK2 (hexokinase 2) as a key regulator of microglial homeostasis, with its expression correlating with microglial migration, proliferation, and inflammation, findings validated in oxygen-glucose deprivation models.
Countstar Connection
Cell-viability assessment in the study's cell samples was performed with Countstar (model not specified) during preparation for single-cell or single-nucleus analysis.
