SCIENTIFIC EVIDENCE

Single-cell multiomics reveals heterogeneous cell states linked to metastatic potential in liver cancer cell lines.

iScience
Wang S, Xie J, Zou X, Pan T, Yu Q, Zhuang Z, Zhong Y, Zhao X, Wang Z, Li R, Lei Y, Yin J, Yuan Y, Wei X, Liu L, Liu S, Yang H, Wu L.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2022
Cancer Research
Immunology
Single-Cell Analysis
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Key Finding
The authors also identified a rare hypoxic subtype that has a higher capacity for glycolysis and exhibits dormant, invasive, and malignant characteristics. The data provide a valuable data resource, facilitate a deeper understanding of metastatic mechanisms, and may help diagnosis of metastatic potential in individual patients, thus supporting personalized medicine.
Countstar Connection
Countstar (model not specified) provided the instrument readout for cell number and viability in the study's cell samples before single-cell analysis for the study's single-cell analysis.
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