Single-cell multi-omics identify novel regulators required for osteoclastogenesis during aging.
iScience
Li H, Xu WX, Tan JC, Hong YM, He J, Zhao BP, Zhou JA, Zheng YM, Lei M, Zheng XQ, Ding J, Liu NN, Gao JJ, Zhang CQ, Wang H.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2024
Single-Cell Analysis
No items found.
Key Finding
The study's analysis revealed that aging significantly instigates OC differentiation. By thoroughly examining the cellular dynamics underpinning bone aging, the study unveils novel insights into the mechanisms of age-related osteoporosis and presents potential therapeutic targets for future exploration.
Countstar Connection
For the study's cell samples, researchers obtained cell-viability measurements with Countstar (model not specified) before single-cell analysis for the study's single-cell analysis.
