SCIENTIFIC EVIDENCE

Single-Cell Landscape Highlights Heterogenous Microenvironment, Novel Immune Reaction Patterns, Potential Biomarkers and Unique Therapeutic Strategies of Cervical Squamous Carcinoma, Human Papillomavirus-Associated (HPVA) and Non-HPVA Adenocarcinoma.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Qiu J, Qu X, Wang Y, Guo C, Lv B, Jiang Q, Su W, Wang L, Hua K.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2023
Cancer Research
Immunology
Microbiology
Single-Cell Analysis
No items found.
Key Finding
Cervical adenocarcinomas (ADCs), including human papillomavirus (HPV)-associated (HPVA) and non-HPVA (NHPVA), though exhibiting a more malignant phenotype and poorer prognosis, are treated identically to squamous cell carcinoma (SCC). Regarding structural cells, the malignancy origin of epithelial cells, angiogenic tip cells and two subtypes of fibroblasts is revealed.
Countstar Connection
In this work, Countstar (model not specified) measured cell viability in the study's cell samples before single-cell analysis for the study's single-cell analysis.
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