Single-cell analysis identifies PI3+S100A7+keratinocytes in early cervical squamous cell carcinoma with HPV infection.
Chinese medical journal
Fan P, Dong D, Feng Y, Zhu X, Wang R.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Cancer Research
Single-Cell Analysis
No items found.
Key Finding
Analysis of clinical information revealed that the infiltration of PI3+S100A7+ keratinocytes was notably higher in tumors with poor prognosis than in those with good prognosis. Moreover, the distinct molecular and cellular differences between HPV16- and HPV66-associated tumors were demonstrated, emphasizing the unique tumor-promoting mechanisms and microenvironmental influences driven by each HPV subtype.
Countstar Connection
Cell-concentration and viability assessment in the study's cell samples used Countstar (model not specified) before single-cell analysis for the study's single-cell analysis.
