Semaglutide Inhibits Osteoblast Ferroptosis Induced by Diabetic Periodontitis via Modulating the Wnt5a/Ror2/p38 MAPK Signaling Pathway.
Drug design, development and therapy
Zhang Z, Niu D, Qiu W, Feng H, Jia L, Zhou W.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2026
Cell Counting & Viability
No items found.
Key Finding
In T2DM periodontitis mice, semaglutide reduced periodontal inflammation and osteoblast ferroptosis. Semaglutide mitigates HGHP-induced osteoblast ferroptosis and improves osteogenic function via the Wnt5a/Ror2/p38 MAPK pathway, supporting its potential in diabetic periodontitis.
Countstar Connection
The study's cell samples underwent cell-count assessment with Countstar (model not specified) during quality assessment for the reported research.
