Role of hepatocyte RIPK1 in maintaining liver homeostasis during metabolic challenges.
eLife
Zhang W, Liu H, Zhang D, Yi Y, Tao L, Zhu Y, Huang S, Zhao X, Shao Q, Li P, Weng Y, Lu W, Zhang J, Zhang H, Chen Y, Weng D.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Single-Cell Analysis
No items found.
Key Finding
Mechanically, the findings indicated that ER stress was involved in fasting-induced liver injury in Ripk1 -hepKO mice. Overall, the findings revealed the role of RIPK1 in maintaining liver homeostasis during metabolic fluctuations and shed light on the intricate interplay between cell death, inflammation, and metabolism.
Countstar Connection
Countstar (model not specified) measured cell concentration and viability in the study's cell samples before single-cell analysis for the reported research.
