Ribosome assembly factor PNO1 is associated with progression and promotes tumorigenesis in triple‑negative breast cancer.

Biological functional studies revealed that transduction of lentivirus encoding sh‑PNO1 significantly downregulated PNO1 expression, reduced cell confluency and the number of BC cells in vitro and inhibited tumor growth in vivo.

For the study's cell samples, researchers obtained cell-count measurements with Countstar (model not specified) during growth assessment for the cancer-model experiments.