Resveratrol Inhibits Insulin-Induced Vascular Smooth Muscle Cell Proliferation and Migration by Activating SIRT1.
Evidence-based complementary and alternative medicine: eCAM
Wang Y, Lei L, Su Q, Qin S, Zhong J, Ni Y, Yang J.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2022
Cell Counting & Viability
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Key Finding
Moreover, resveratrol treatment increased SIRT1 protein expression in VSMCs. The study revealed that treatment with resveratrol inhibited insulin-mediated VSMC proliferation and migration, possibly by activating SIRT1 and downregulating the PI3K/AKT pathway.
Countstar Connection
The research used Countstar (model not specified) for cell-count assessment in the study's cell samples during migration assessment for the reported research.