PVT1 Mediates Cell Proliferation, Apoptosis and Radioresistance in Nasopharyngeal Carcinoma Through Regulating miR-515-5p/PIK3CA Axis.
Cancer management and research
Han Y, Li F, Xie J, Wang Y, Zhang H.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2020
Cancer Research
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Key Finding
Xenograft tumor model was established to investigate the biological role of PVT1 in vivo. Further studies indicated that PVT1 regulated radioresistance via miR-515-5p/PIK3CA axis and modulated the AKT pathway by interacting with miR-515-5p.
Countstar Connection
Researchers used Countstar (model not specified) to assess flow-cytometry cell measurements in the study's cell samples during growth assessment in the 2020 Cancer management and research study.
