SCIENTIFIC EVIDENCE

PTH (1-34) enhances the therapeutic effect of bone marrow mesenchymal stem cell-derived exosomes by inhibiting proinflammatory cytokines expression on OA chondrocyte repair in vitro.

Arthritis research & therapy
Shao LT, Luo L, Qiu JH, Deng DYB.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2022
Bioprocessing
Stem Cell Research
No items found.
Key Finding
The study showed that IL-2, TNF-α, and IL-6 levels increased significantly in OA chondrocytes; however, both Exo BMSC and Exo PTH reduced the levels of IL-2, TNF-α, and IL-6. Exo PTH increased the migration, proliferation, and chondral matrix formation of OA chondrocytes in vitro.
Countstar Connection
Countstar (model not specified) generated cell-concentration measurements for the study's cell samples during quality assessment for the immune-cell research.
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