Preclinical Study of Plasmodium Immunotherapy Combined with Radiotherapy for Solid Tumors.
Cells
Tao Z, Ding W, Cheng Z, Feng Y, Kang Z, Qiu R, Zhao S, Hu W, Zhou F, Wu D, Duan Z, Qin L, Chen X.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2022
Cancer Research
Immunology
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Key Finding
By analyzing the immune profile of the tumor tissues, the authors found that the combination therapy was more effective in upregulating the perforin-expressing effector CD8 + T cells and downregulating the myeloid-derived suppressor cells (MDSCs), and was thus more effective in the treatment of cancer.
Countstar Connection
A Countstar instrument measured cell numbers in the study's cell samples before single-cell analysis for the cancer-model experiments.
