Platelet Mitochondria Transplantation Rescues Hypoxia/Reoxygenation-Induced Mitochondrial Dysfunction and Neuronal Cell Death Involving the FUNDC2/PIP3/Akt/FOXO3a Axis.
Cell transplantation
Shi C, Guo H, Liu X.
Publication Overview
Key findings, Countstar context, and access to the original paper.
The showed that incorporation of human plt-mito into SH-SY5Y cells rescued HR-induced mitochondrial malfunction and mitochondrial apoptotic pathway. Mechanistically, plt-mito transplantation led to an increased expression of FUNDC2 in the recipient cells.
Countstar Connection
A Countstar instrument was the instrument used to assess sample absorbance in the study's cell samples during sample-quality assessment.
