Plasma cells shape the mesenchymal identity of ovarian cancers through transfer of exosome-derived microRNAs.
Science advances
Yang Z, Wang W, Zhao L, Wang X, Gimple RC, Xu L, Wang Y, Rich JN, Zhou S.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2021
Cancer Research
Immunology
Stem Cell Research
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Key Finding
Plasma cell abundance correlated with the density of mesenchymal cells in clinical specimens of HGSCs. Collectively, the work suggests targeting plasma cells may be a novel approach for ovarian cancer therapy.
Countstar Connection
Within the study, Countstar (model not specified) measured cell numbers in the study's cell samples during the study's migration assessment.
