Co-administration of pirfenidone with PD-L1 blockades significantly delayed the tumor growth and increased survival, compared with the effect of either treatment alone. Combination therapy promoted gene expression with a unique signature associated with innate and adaptive immune response ed in the infiltration of immune cells and optimal T cell positioning.
Countstar Connection
The study obtained flow-cytometry measurements from the study's cell samples using Countstar (model not specified) during preparation for downstream cell analysis.