SCIENTIFIC EVIDENCE

Pilot-scale process development for recombinant adeno-associated virus (rAAV) production based on high-density Sf9 cell culture.

Virology journal
Li X, Gu J, Wu H, Xie Y.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2024
Bioprocessing
Microbiology
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Key Finding
On the basis of the equal P/V principle and considering the problem posed by air bubbles, a pilot-scale level bioreactor process was established. By resolving the problems associated with high-density cell culture and air bubbles, this process was successfully scaled to a 50 L pilot-scale level.
Countstar Connection
A Countstar instrument supported assessment of cell concentration and viability in the study's cell samples during culture monitoring in the 2024 Virology journal study.
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