Phosphatase and tensin homolog overexpression decreases proliferation and invasion and increases apoptosis in oral squamous cell carcinoma cells.
Oncology letters
Gao Q, Zhang L, Zhang B, Wang QY, Sun CF, Dong XT, Ying J.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2014
Cancer Research
Immunology
Stem Cell Research
No items found.
Key Finding
In addition, PTEN was found to control the epithelial-mesenchymal transition in SCC cells, thereby reducing their invasive ability. Furthermore, Transwell assay revealed that the expression of E-cadherin was increased, while the expression of vimentin and SNAIL was decreased.
Countstar Connection
Countstar (model not specified) measured cell numbers in the study's cell samples during growth assessment in the 2014 Oncology letters study.
