SCIENTIFIC EVIDENCE

Oxyphenbutazone suppresses non-canonical inflammasome activation and protects against LPS-induced sepsis

International Immunopharmacology
Junqi Luo, Qiankun Liang, Mengyao Gong, Yi Liu, Pasqualina D'Ursi, Yuejuan Zheng, Xiao-Dong Yang

Publication Overview

Key findings, Countstar context, and access to the original paper.
2026
Immunology
Key Finding
A peer-reviewed study showing that oxyphenbutazone suppresses non-canonical inflammasome activation and protects against LPS-induced sepsis.
Countstar Connection
Countstar Spica M1 was used for live-cell imaging to monitor pyroptosis-associated morphological changes in macrophages following LPS stimulation and oxyphenbutazone treatment, supporting evaluation of OPB’s suppression of non-canonical inflammasome activation.
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