SCIENTIFIC EVIDENCE

Optimized Antimicrobial Peptide Jelleine-I Derivative Br-J-I Inhibits Fusobacterium Nucleatum to Suppress Colorectal Cancer Progression.

International journal of molecular sciences
Jia F, Yu Q, Wang R, Zhao L, Yuan F, Guo H, Guo H, Shen Y, He F.

Publication Overview

Key findings, Countstar context, and access to the original paper.
2023
Cancer Research
Microbiology
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Key Finding
The findings show that Br-J-I showed the highest anti- Fn activity and Br-J-I may target membrane-associated FadA for Fn membrane disruption. These suggest that Br-J-I could be considered as an adjunctive agent for CRC treatment and AMPs-based combination treatment is a new strategy for CRC in the future.
Countstar Connection
The study obtained cell-count measurements from the study's cell samples with Countstar (model not specified) during growth assessment in the 2023 International journal of molecular sciences study.
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