Optimization of a novel expression system for recombinant protein production in CHO cells.
Scientific reports
Zhang J, Du C, Pan Y, Zhang Z, Feng R, Ma M, Wang T.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2024
Bioprocessing
No items found.
Key Finding
Therefore, the vector was optimized by adding regulatory elements, and the cell line was modified by using CRISPR/Cas9 technology to establish a novel CHO cell expression system, which remarkably improved the expression level of recombinant proteins and laid the foundation for the large-scale production of recombinant proteins.
Countstar Connection
The study used Countstar (model not specified) for cell-viability assessment in the study's cell samples during quality assessment in the 2024 Scientific reports study.
