NFS1, together with FXN, protects cells from ferroptosis and DNA damage in diffuse large B-cell lymphoma.
Redox biology
Shi X, Zhao Y, Gao HY, Yang W, Liao J, Wang HH, Wang XT, Yan W.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2025
Cancer Research
Cell Counting & Viability
Immunology
No items found.
Key Finding
Consistent with NFS1, FXN silencing aggravated erastin-induced cell viability inhibition and LDH level enhancement. The authors demonstrated that ISC-related proteins NFS1 and FXN protect DLBCL cells from ferroptosis and DNA damage, thus exhibiting an essential role in DLBCL progression.
Countstar Connection
Cell-count assessment in the study's cell samples was performed with Countstar (model not specified) during cell-culture monitoring.
