New Insight into Polydopamine@ZIF-8 Nanohybrids: A Zinc-Releasing Container for Potential Anticancer Activity.
Polymers
Ran J, Wang C, Zhang J, Wang W, Xiao L, Jia S, Wang Z, Wu W, Xiao J, Wu X.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2018
Cancer Research
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Key Finding
Transmission electron microscopy (TEM) analysis demonstrated that the ZIF-8 nanocrystals were gradually etched out in the aqueous media within 48 h, resulting in hollow nanocapsules. Notably, the authors found the self-polymerization of dopamine can form nanoshells around the ZIF-8 nanocrystals, which served as a type of functional membranes during the release of zinc.
Countstar Connection
Cell-count assessment in the study's cell samples was performed with a Countstar instrument during treatment-response assessment.