Chu C, Wang X, Yang C, Chen F, Shi L, Xu W, Wang K, Liu B, Wang C, Sun D, Ding W.
Publication Overview
Key findings, Countstar context, and access to the original paper.
2023
Immunology
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Key Finding
However, the administration of the ferroptosis inhibitor ferrostatin-1 or the inhibition of NETs via neutrophil-specific peptidylarginine deiminase 4 (Pad4) deficiency led to positive outcomes, with reduced intestinal endothelial ferroptosis and microvascular function recovery. Moreover, RNA-seq analysis revealed a significant enrichment of mitophagy- and ferroptosis-related signaling pathways in HUVECs incubated with NETs.
Countstar Connection
Researchers relied on a Countstar instrument for cell-count measurements in the study's cell samples during quality assessment in the 2023 Redox biology study.
